Captopril and Hypertension (Topics in Cardiovascular by David Case

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By David Case

This monograph used to be constructed from a set of papers that have been origi­ nally provided at a symposium entitled "Pathogenesis of high blood pressure" held on the Henry Chauncy convention heart, Princeton. New Jersey. those manuscripts have been consequently revised, up-to-date, and reorganized in a way appropriate for this book. The symposium was once deliberate to stimu­ overdue curiosity between investigators and clinicians alike within the strength for a brand new category of substances referred to as changing enzyme inhibitors in scientific medication. The assembly was once subsidized via the Squibb Institute for clinical study, whose pioneering biochemical and pharmaceutical study had resulted in the improvement of the 1st orally lively changing enzyme inhibitor. it's was hoping that this monograph will cohesively pull jointly the thesis that the identity, quantification, and containment of the renin think about high blood pressure could be a robust diagnostic and healing technique in medical drugs. additionally, the series of stories provided during this manuscript will serve to illustrate how simple biochemical and physio­ logical learn produces primary and significant details on which next significant advances in scientific pharmacology and drugs might be based.

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